AHS19 has ended
Back To Schedule
Saturday, August 10 • 9:50am - 10:30am
Physiological Basis of the Endocannabinoid System, and Phytocannabinoids.

Sign up or log in to save this to your schedule, view media, leave feedback and see who's attending!

The purpose of this talk is to provide a physiological basis for understanding the function of the ECS and how genetics and diet influence endocannabinoid tone. From the physiological basis of the ECS this presentation will build upon the pharmacology and pharmacogenomics to provide rationale for determining the most effective clinical approach to endocannabinoid therapies. Polymorphisms in the genes for the component enzymes and receptors of the ECS can influence the clinical outcome of cannabinoid therapies. One poignant example of this are ultra-fast variants of CYP2C9 are poor candidates for oral consumption of Delta-9-THC due to the rapid conversion of Delta-9-THC into 11-OH-THC. 11-OH-THC is poorly tolerated due to intensity of euphoric effect and long terminal plasma half-life (up to 72 hours).

avatar for Steve Ottersberg

Steve Ottersberg

Education: B.S. Biochemistry, Fort Lewis College, Durango CO. Undergraduate research focus on insect pheromone analog design and synthesis. Natural products chemistry was at the top of academic interests, so terpenoids and cannabinoids were part of research. M.S. (ABD) in Biochemistry... Read More →

Saturday August 10, 2019 9:50am - 10:30am PDT
West Ballroom B